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Searches using filters for organ/system affected are limited to effects (or tumor sites) used to derive the RfD, RfC, oral slope factor, or inhalation unit risk. Other effects associated with chemicals in the IRIS database that were not used as the basis for a toxicity value are not searchable with organ/system filters. IRIS Advanced Search searches only final IRIS assessments; to look for information on draft assessments, see Quick Check: Assessments in Development.

Search Filtered by: Tumor Site = "Urinary"
Number of records: 18
Chemical Name CASRN Exposure Route WOE Characterization Tumor Type Toxicity Value
Benzidine 92-87-5 Inhalation A (Human carcinogen) (1986 guidelines)
Bladder tumors 6.7 x 10 -2 per µg/m3
Benzidine 92-87-5 Oral A (Human carcinogen) (1986 guidelines)
Bladder tumors 6.7 x 10 -3 per µg/L
Bromate 15541-45-4 Oral B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) (1986 guidelines)
Carcinogenic potential cannot be determined (1996 guidelines)
Known/likely human carcinogen (1996 guidelines)
Testicular mesothelioma, renal tubular adenoma and carcinoma, and thyroid follicular cell adenoma and carcinoma 2 x 10 -5 per µg/L
Bromodichloromethane 75-27-4 Oral B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) (1986 guidelines)
Kidney (tubular cell adenoma and tubular cell adenocarcinoma) 1.8 x 10 -6 per µg/L
1,3-Dichloropropene 542-75-6 Oral B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) (1986 guidelines)
Known/likely human carcinogen (1996 guidelines)
Urinary bladder carcinoma 3 x 10 -6 per µg/L
1,4-Dioxane 123-91-1 Inhalation Likely to be carcinogenic to humans (2005 guidelines)
Multiple (nasal, liver, kidney, peritoneal, mammary gland, and Zymbal gland) 5 x 10 -6 per µg/m3
Hexachlorobutadiene 87-68-3 Oral C (Possible human carcinogen) (1986 guidelines)
Renal tubular adenomas and adenocarcinomas 2.2 x 10 -6 per µg/L
Hexachlorobutadiene 87-68-3 Inhalation C (Possible human carcinogen) (1986 guidelines)
Renal tubular adenomas and adenocarcinomas 2.2 x 10 -5 per µg/m3
Hexachloroethane 67-72-1 Oral Likely to be carcinogenic to humans (2005 guidelines)
Renal adenomas and carcinomas (combined) 1 x 10 -6 per µg/L
Nitrobenzene 98-95-3 Inhalation Likely to be carcinogenic to humans (2005 guidelines)
Liver hepatocellular adenomas or carcinomas, kidney tubular adenomas or carcinomas, thyroid follicular cell adenomas or carcinomas 4 x 10 -5 per µg/m3
N-Nitroso-di-n-butylamine 924-16-3 Oral B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) (1986 guidelines)
Bladder and esophagus tumors 1.6 x 10 -4 per µg/L
N-Nitroso-di-n-butylamine 924-16-3 Inhalation B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) (1986 guidelines)
Bladder and esophagus tumors 1.6 x 10 -3 per µg/m3
N-Nitrosodiphenylamine 86-30-6 Oral B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) (1986 guidelines)
Transitional cell carcinoma of the bladder 1.4 x 10 -7 per µg/L
Trichloroethylene 79-01-6 Oral Carcinogenic to humans (2005 guidelines)
Renal cell carcinoma, non-Hodgkin's lymphoma, and liver tumors
Trichloroethylene 79-01-6 Inhalation Carcinogenic to humans (2005 guidelines)
Renal cell carcinoma, non-Hodgkin's lymphoma, and liver tumors 4.1 x 10 -6 per µg/m3
Trifluralin 1582-09-8 Oral C (Possible human carcinogen) (1986 guidelines)
Combined renal pelvis carcinomas, urinary bladder papillomas and/or thyroid adenomas and carcinomas 2.2 x 10 -7 per µg/L
2,4,6-Trinitrotoluene (TNT) 118-96-7 Oral C (Possible human carcinogen) (1986 guidelines)
Urinary bladder, transitional cell papilloma and transitional squamous cell carcinomas 9.0 x 10 -7 per µg/L
tert-Butyl Alcohol (tBA) 75-65-0 Oral Suggestive evidence of carcinogenic potential (2005 guidelines)
Renal adenomas and carcinomas, thyroid adenomas