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Searches using filters for organ/system affected are limited to effects (or tumor sites) used to derive the RfD, RfC, oral slope factor, or inhalation unit risk. Other effects associated with chemicals in the IRIS database that were not used as the basis for a toxicity value are not searchable with organ/system filters. IRIS Advanced Search searches only final IRIS assessments; to look for information on draft assessments, see Quick Check: Assessments in Development. Additional information can be downloaded below by clicking on the “Export to Excel” feature.

Chemical Revision History

A basic version of this table is available.
ROW CHEMICAL NAME CASRN REVISION NUMBER REVISION DATE SECTIONS REVISED REVISION DESCRIPTION
1 Acenaphthene 83-32-9 1 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
2 Acenaphthene 83-32-9 2 19950801 Aug 1,1995 II. EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS review. The IRIS Pilot Program replaced the workgroup functions beginning in September, 1995.
3 Acenaphthene 83-32-9 3 20190311 Mar 11,2019 Nanocancer RfD Clean Corrected a typo on the RfD POD value and also removed the adjusted 05 settings on the data entry form by request from S.Rieth.
4 Acenaphthene 83-32-9 4 20200714 Jul 14,2020 Related Topics Added Chemicals Dashboard link
5 Acenaphthylene 208-96-8 1 20200714 Jul 14,2020 Related Topics Added Chemicals Dashboard link
6 Acephate 30560-19-1 1 20160715 Jul 15,2016 Archiveed Assessment IRIS working with OPP agreed to mark this pesticide chemical archived.
7 Acephate 30560-19-1 4 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
8 Acetaldehyde 75-07-0 1 None None
9 Acetaldehyde 75-07-0 2 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
10 Acetochlor 34256-82-1 1 19910801 Aug 1,1991 I.A. Oral RfD now under review
11 Acetochlor 34256-82-1 2 19910801 Aug 1,1991 II. Carcinogenicity assessment now under review
12 Acetochlor 34256-82-1 3 19930901 Sep 1,1993 I.A. Oral RfD on-line
13 Acetochlor 34256-82-1 4 19930901 Sep 1,1993 VI.A. Oral RfD references on-line
14 Acetochlor 34256-82-1 5 19950801 Aug 1,1995 II. EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS review. The IRIS Pilot Program replaced the workgroup functions beginning in September, 1995.
15 Acetochlor 34256-82-1 6 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
16 Acetochlor 34256-82-1 7 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
17 Acetone 67-64-1 1 19880301 Mar 1,1988 I.A.5. Confidence levels revised
18 Acetone 67-64-1 2 19890701 Jul 1,1989 VI. Bibliography on-line
19 Acetone 67-64-1 3 19900101 Jan 1,1990 II. Carcinogen assessment now under review
20 Acetone 67-64-1 4 19900701 Jul 1,1990 II. Carcinogen assessment on-line
21 Acetone 67-64-1 5 19900701 Jul 1,1990 IV.F.1. EPA contact changed
22 Acetone 67-64-1 6 19900701 Jul 1,1990 VI.C. Carcinogen references added
23 Acetone 67-64-1 7 19901201 Dec 1,1990 I.A.2. Text edited
24 Acetone 67-64-1 8 19901201 Dec 1,1990 I.A.7. Regulatory actions updated
25 Acetone 67-64-1 9 19901201 Dec 1,1990 II.A.4. Text edited
26 Acetone 67-64-1 10 19920101 Jan 1,1992 IV. Regulatory actions updated
27 Acetone 67-64-1 11 19930801 Aug 1,1993 I.A. Oral RfD noted as pending change
28 Acetone 67-64-1 12 19930801 Aug 1,1993 I.A.6. Work group review date added
29 Acetone 67-64-1 13 19950801 Aug 1,1995 I.A., I.A.6. EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS review. The IRIS Piot Program replaced the workgroup functions beginning in September, 1995.
30 Acetone 67-64-1 14 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
31 Acetone 67-64-1 15 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
32 Acetonitrile 75-05-8 1 19880630 Jun 30,1988 I.A.2. Principal study clarified
33 Acetonitrile 75-05-8 2 19890701 Jul 1,1989 I.B. Inhalation RfD now under review
34 Acetonitrile 75-05-8 3 19890801 Aug 1,1989 I.A. Oral RfD summary noted as pending change
35 Acetonitrile 75-05-8 4 19900201 Feb 1,1990 I.A. Hazelton Labs, 1983 corrected to NTP, 1983
36 Acetonitrile 75-05-8 5 19900201 Feb 1,1990 I.A.2. Text clarified (paragraph 4)
37 Acetonitrile 75-05-8 6 19900201 Feb 1,1990 VI. Bibliography on-line
38 Acetonitrile 75-05-8 7 19900301 Mar 1,1990 VI.A. NTP, 1983 - strain of rats and mice clarified
39 Acetonitrile 75-05-8 8 19920101 Jan 1,1992 I.A.7. Secondary contact changed
40 Acetonitrile 75-05-8 9 19920101 Jan 1,1992 IV. Regulatory actions updated
41 Acetonitrile 75-05-8 10 19960201 Feb 1,1996 I.A.7. Secondary contact deleted
42 Acetonitrile 75-05-8 11 19990303 Mar 3,1999 I., II., VI. RfD withdrawn, discussion added; new RfC and cancer assessment
43 Acetonitrile 75-05-8 12 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
44 Acetophenone 98-86-2 1 19880822 Aug 22,1988 I.A. oral RfD summary on-line
45 Acetophenone 98-86-2 2 19890101 Jan 1,1989 I.A.7. Contacts phone numbers corrected
46 Acetophenone 98-86-2 3 19890801 Aug 1,1989 VI. Bibliography on-line
47 Acetophenone 98-86-2 4 19901201 Dec 1,1990 II. Carcinogen assessment now under review
48 Acetophenone 98-86-2 5 19910201 Feb 1,1991 II. Carcinogenicity assessment on-line
49 Acetophenone 98-86-2 6 19910201 Feb 1,1991 VI.C. Carcinogen references added
50 Acetophenone 98-86-2 7 19910901 Sep 1,1991 I.B. Inhalation RfC now under review
51 Acetophenone 98-86-2 8 19920101 Jan 1,1992 I.A.7. Secondary contact changed
52 Acetophenone 98-86-2 9 19920101 Jan 1,1992 IV. Regulatory Action section on-line
53 Acetophenone 98-86-2 10 19920801 Aug 1,1992 I.B. Work group review meeting date added
54 Acetophenone 98-86-2 11 19950801 Aug 1,1995 I.B. EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS review. The IRIS Pilot Program replaced the workgroup functions beginning in September, 1995.
55 Acetophenone 98-86-2 12 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Office for this information.
56 Acetophenone 98-86-2 13 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
57 Acetyl chloride 75-36-5 1 19910301 Mar 1,1991 II. Carcinogenicity assessment on-line
58 Acetyl chloride 75-36-5 2 19910301 Mar 1,1991 VI. Bibliography on-line
59 Acetyl chloride 75-36-5 3 19920101 Jan 1,1992 IV. Regulatory Action section on-line
60 Acetyl chloride 75-36-5 5 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
61 Acetyl chloride 75-36-5 6 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
62 Acifluorfen, sodium 62476-59-9 1 19881201 Dec 1,1988 I.A.2. Text revised
63 Acifluorfen, sodium 62476-59-9 2 19891101 Nov 1,1989 VI. Bibliography on-line
64 Acifluorfen, sodium 62476-59-9 3 19901001 Oct 1,1990 III.A. Health Advisory on-line
65 Acifluorfen, sodium 62476-59-9 4 19901001 Oct 1,1990 VI.D. Health Advisory references added
66 Acifluorfen, sodium 62476-59-9 5 19931101 Nov 1,1993 II. Work group review date added
67 Acifluorfen, sodium 62476-59-9 6 19950801 Aug 1,1995 II. EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS review. The IRIS Pilot Program replaced the workgroup functions beginning in September, 1995.
68 Acifluorfen, sodium 62476-59-9 7 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
69 Acrolein 107-02-8 1 19880907 Sep 7,1988 II. Carcinogen summary on-line
70 Acrolein 107-02-8 2 19890401 Apr 1,1989 V. Supplementary data on-line
71 Acrolein 107-02-8 3 19890701 Jul 1,1989 I.B. Inhalation RfD now under review
72 Acrolein 107-02-8 4 19900301 Mar 1,1990 II.A.4. Citations clarified (3rd paragraph)
73 Acrolein 107-02-8 5 19900301 Mar 1,1990 VI. Bibliography on-line
74 Acrolein 107-02-8 6 19900501 May 1,1990 VI.C. Hemminki et al., 1980 citation corrected
75 Acrolein 107-02-8 7 19911001 Oct 1,1991 I.B. Inhalation RfC summary on-line
76 Acrolein 107-02-8 8 19911001 Oct 1,1991 I.B. Inhalation RfC references added
77 Acrolein 107-02-8 9 19920101 Jan 1,1992 IV. Regulatory Action section on-line
78 Acrolein 107-02-8 10 19930701 Jul 1,1993 I.B.1. LOAEL (ADJ) corrected
79 Acrolein 107-02-8 11 19940201 Feb 1,1994 II.D.3. Secondary contact's phone number changed
80 Acrolein 107-02-8 12 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
81 Acrolein 107-02-8 13 20190311 Mar 11,2019 Nanocancer RfD Clean Removed Adjusted and 05 from the RfD table, per request from S. Rieth.
82 Acrolein 107-02-8 14 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
83 Acrylamide 79-06-1 1 19880926 Sep 26,1988 I.A. Oral RfD summary on-line
84 Acrylamide 79-06-1 2 19880926 Sep 26,1988 II. Carcionogen summary on-line
85 Acrylamide 79-06-1 3 19890601 Jun 1,1989 II.D.2. Work group review date added
86 Acrylamide 79-06-1 4 19900901 Sep 1,1990 II. Text edited
87 Acrylamide 79-06-1 5 19900901 Sep 1,1990 III.A. Health Advisory on-line
88 Acrylamide 79-06-1 6 19900901 Sep 1,1990 VI. Bibliography on-line
89 Acrylamide 79-06-1 7 19901001 Oct 1,1990 I.B. Not verified data inadequate
90 Acrylamide 79-06-1 8 19901101 Nov 1,1990 I.B. Inhalation RfC message on-line
91 Acrylamide 79-06-1 9 19901101 Nov 1,1990 VI.B. Inhalation RfC references on-line
92 Acrylamide 79-06-1 10 19910101 Jan 1,1991 II. Text edited
93 Acrylamide 79-06-1 11 19910101 Jan 1,1991 II.C.1. Inhalation slope factor removed (global change)
94 Acrylamide 79-06-1 12 19910301 Mar 1,1991 I.A.5. Database corrected to medium text revised
95 Acrylamide 79-06-1 13 19910801 Aug 1,1991 VI.C. References clarified
96 Acrylamide 79-06-1 14 19920101 Jan 1,1992 IV. Regulatory Action section on-line
97 Acrylamide 79-06-1 15 19930701 Jul 1,1993 II.D.1. Source document and review statement clarified
98 Acrylamide 79-06-1 16 19950801 Aug 1,1995 II.D.2 EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS review. The IRIS Pilot Program replaced the workgroup functions beginning in September, 1995.
99 Acrylamide 79-06-1 17 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
100 Acrylamide 79-06-1 18 20010222 Feb 22,2001 I., II. This chemical is being reassessed under the IRIS Program.
101 Acrylamide 79-06-1 19 20100316 Mar 16,2010 I., II., VI. RfD and cancer assessment sections updated, RfC assessment added.
102 Acrylamide 79-06-1 20 20110309 Mar 9,2011 NA Corrections that were made to Table 3-2 of the Toxicological Review of Acrylamide: 1. Some of the superscripts were missing or wrong. 2. The species "hamster" should be "humans". 3. Citaion "j" Fennell et al 2005 should be Fennell et al 2006 4. All citations for Hartmann et al., 2008, 224480 should be Kopp and Dekant, 2009, 224532
103 Acrylamide 79-06-1 21 20180710 Jul 10,2018 Key Values Table A footnote was added for ADAF.
104 Acrylamide 79-06-1 22 20200714 Jul 14,2020 Related Topics Added Chemicals Dashboard link
105 Acrylic acid 79-10-7 1 19880301 Mar 1,1988 I.A.5. Confidence levels revised
106 Acrylic acid 79-10-7 2 19870331 Mar 31,1987 I.A.6. Documentation corrected
107 Acrylic acid 79-10-7 3 19880301 Mar 1,1988 I.A.2. Paragraph 3 deleted
108 Acrylic acid 79-10-7 4 19890801 Aug 1,1989 VI. Bibliography on-line
109 Acrylic acid 79-10-7 5 19900901 Sep 1,1990 I.B. Inhalation RfC now under review
110 Acrylic acid 79-10-7 6 19901001 Oct 1,1990 I.B. Inhalation RfC summary on-line
111 Acrylic acid 79-10-7 7 19901001 Oct 1,1990 VI.B. Inhalation RfC references added
112 Acrylic acid 79-10-7 8 19920101 Jan 1,1992 I.A.7. Primary contact changed
113 Acrylic acid 79-10-7 9 19920101 Jan 1,1992 IV. Regulatory actions updated
114 Acrylic acid 79-10-7 10 19940301 Mar 1,1994 I.A. Withdrawn; new oral RfD verified (in preparation)
115 Acrylic acid 79-10-7 11 19940301 Mar 1,1994 I.B. Withdrawn; new inhalation RfC verified (in preparation)
116 Acrylic acid 79-10-7 12 19940301 Mar 1,1994 VI. Bibliography withdrawn
117 Acrylic acid 79-10-7 13 19940401 Apr 1,1994 I.A. Oral RfD summary replaced; new RfD
118 Acrylic acid 79-10-7 14 19940401 Apr 1,1994 I.B. Inhalation RfC summary replaced; new RfC
119 Acrylic acid 79-10-7 15 19940401 Apr 1,1994 VI.A. Oral RfD references replaced
120 Acrylic acid 79-10-7 16 19940401 Apr 1,1994 VI.B. Inhalation RfC references replaced
121 Acrylic acid 79-10-7 17 19940501 May 1,1994 I.A.2. Note moved from Add. Com. Sec. to Prin. Sup. Stud. Sec
122 Acrylic acid 79-10-7 18 19940501 May 1,1994 I.B.1. Note moved from Add. Com. Sec. to Prin. Sup. Stud. Sec
123 Acrylic acid 79-10-7 19 19950501 May 1,1995 I.B.4. Text edited (9th paragraph)
124 Acrylic acid 79-10-7 20 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
125 Acrylic acid 79-10-7 21 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
126 Acrylonitrile 107-13-1 1 19880301 Mar 1,1988 II.B.4. Confidence statement revised
127 Acrylonitrile 107-13-1 2 19890201 Feb 1,1989 II.D.3 Secondary contact's phone number corrected
128 Acrylonitrile 107-13-1 3 19890701 Jul 1,1989 II. Citations for Quast et al. clarified
129 Acrylonitrile 107-13-1 4 19890701 Jul 1,1989 VI. Bibliography on-line
130 Acrylonitrile 107-13-1 5 19900601 Jun 1,1990 IV.A.1. Area code for EPA contact corrected
131 Acrylonitrile 107-13-1 6 19900601 Jun 1,1990 IV.F.1. EPA contact changed
132 Acrylonitrile 107-13-1 7 19910101 Jan 1,1991 I.B. Inhalation RfC now under review
133 Acrylonitrile 107-13-1 8 19910101 Jan 1,1991 II. Text edited
134 Acrylonitrile 107-13-1 9 19910101 Jan 1,1991 II.C.1. Inhalation slope factor removed (global change)
135 Acrylonitrile 107-13-1 10 19911101 Nov 1,1991 I.B. Inhalation RfC summary on-line
136 Acrylonitrile 107-13-1 11 19911101 Nov 1,1991 VI.B. Inhalation RfC references added
137 Acrylonitrile 107-13-1 12 19911201 Dec 1,1991 I.B. Text edited
138 Acrylonitrile 107-13-1 13 19920101 Jan 1,1992 IV. Regulatory actions updated
139 Acrylonitrile 107-13-1 14 19920401 Apr 1,1992 IV.A.1. CAA regulatory action withdrawn
140 Acrylonitrile 107-13-1 15 19920801 Aug 1,1992 I.A. Oral RfD now under review
141 Acrylonitrile 107-13-1 16 19930701 Jul 1,1993 I.A. Work group review date added
142 Acrylonitrile 107-13-1 17 19950801 Aug 1,1995 I.A. EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by the Program replaced the workgroup functions beginning in September, 1995.
143 Acrylonitrile 107-13-1 18 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
144 Acrylonitrile 107-13-1 19 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
145 Adiponitrile 111-69-3 1 19910201 Feb 1,1991 II. Carcinogenicity assessment on-line
146 Adiponitrile 111-69-3 2 19910201 Feb 1,1991 VI. Bibliography on-line
147 Adiponitrile 111-69-3 3 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
148 Adiponitrile 111-69-3 4 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
149 Alachlor 15972-60-8 1 19880301 Mar 1,1988 III.A. Health Advisory added
150 Alachlor 15972-60-8 2 19881201 Dec 1,1988 I.A.4. Core graded added to studies 1, 3 and 4
151 Alachlor 15972-60-8 3 19891101 Nov 1,1989 VI. Bibliography on-line
152 Alachlor 15972-60-8 4 19920101 Jan 1,1992 IV. Regulatory actions updated
153 Alachlor 15972-60-8 5 19930901 Sep 1,1993 I.A. Oral RfD revised; same study and number
154 Alachlor 15972-60-8 6 19931101 Nov 1,1993 III.A.2. Ten-day Health Advisory corrected
155 Alachlor 15972-60-8 7 19931101 Nov 1,1993 III.A.9. Documentation revised
156 Alachlor 15972-60-8 8 19931101 Nov 1,1993 IV.B.2. Discussion corrected
157 Alachlor 15972-60-8 9 19931101 Nov 1,1993 VI. Health Advisory references revised
158 Alachlor 15972-60-8 10 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions,and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
159 Alachlor 15972-60-8 11 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
160 Alar 1596-84-5 1 19880822 Aug 22,1988 I.A.4. Study 4 text revised
161 Alar 1596-84-5 2 19910201 Feb 1,1991 I.B. Incorrect message removed
162 Alar 1596-84-5 3 19910701 Jul 1,1991 I.A. Principal study clarified
163 Alar 1596-84-5 4 19910701 Jul 1,1991 I.A.4. Citations clarified
164 Alar 1596-84-5 5 19910701 Jul 1,1991 VI. Bibliography on-line
165 Alar 1596-84-5 6 19920101 Jan 1,1992 IV. Regulatory Action section on-line
166 Alar 1596-84-5 7 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
167 Alar 1596-84-5 8 20180927 Sep 27,2018 Noncancer Critical Updated the system from none to other so it would show up in the advanced search.
168 Alar 1596-84-5 9 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
169 Aldicarb 116-06-3 1 19880301 Mar 1,1988 I.A.5. Confidence levels revised
170 Aldicarb 116-06-3 2 19880301 Mar 1,1988 I.A.7. Primary contact changed
171 Aldicarb 116-06-3 3 19880301 Mar 1,1988 III.A. Health Advisory added
172 Aldicarb 116-06-3 4 19880822 Aug 22,1988 II. Carcinogen summary on-line
173 Aldicarb 116-06-3 5 19890501 May 1,1989 I.A.5. Confidence statement revised
174 Aldicarb 116-06-3 6 19890501 May 1,1989 I.A.7. Secondary contact changed
175 Aldicarb 116-06-3 7 19890601 Jun 1,1989 II.D.2. Work group review date added
176 Aldicarb 116-06-3 8 19890801 Aug 1,1989 VI. Bibliography on-line
177 Aldicarb 116-06-3 9 19900701 Jul 1,1990 I.A. Oral RfD summary noted as pending change
178 Aldicarb 116-06-3 10 19900801 Aug 1,1990 I.A. Withdrawn; new Oral RfD verified (in preparation)
179 Aldicarb 116-06-3 11 19900801 Aug 1,1990 III.A.5. DWEL & Lifetime HA withdrawn (RfD withdrawn)
180 Aldicarb 116-06-3 12 19900801 Aug 1,1990 VI.A. Oral RfD references withdrawn
181 Aldicarb 116-06-3 13 19910301 Mar 1,1991 II.D.3 Secondary contact changed
182 Aldicarb 116-06-3 14 19910701 Jul 1,1991 I.A. Oral RfD summary replaced; RfD changed
183 Aldicarb 116-06-3 15 19910701 Jul 1,1991 III.A.5. DWEL and Lifetime HA replaced
184 Aldicarb 116-06-3 16 19910701 Jul 1,1991 VI.A. Oral RfD references replaced
185 Aldicarb 116-06-3 17 19910701 Jul 1,1991 III.A. Section III.A.1-4 replaced
186 Aldicarb 116-06-3 18 19910801 Aug 1,1991 I.A. General edit
187 Aldicarb 116-06-3 19 19920101 Jan 1,1992 IV. Regulatory actions updated
188 Aldicarb 116-06-3 20 19921001 Oct 1,1992 I.A. Oral RfD summary noted as pending change
189 Aldicarb 116-06-3 21 19921001 Oct 1,1992 I.A.6. Work group review date added
190 Aldicarb 116-06-3 22 19921201 Dec 1,1992 I.A.6. Work group review date added
191 Aldicarb 116-06-3 23 19931101 Nov 1,1993 I.A. Oral RfD summary replaced; new RfD
192 Aldicarb 116-06-3 24 19931101 Nov 1,1993 III.A. Health Advisory withdrawn
193 Aldicarb 116-06-3 25 19931101 Nov 1,1993 VI.A. Oral RfD references replaced
194 Aldicarb 116-06-3 26 19931101 Nov 1,1993 VI.D. Health Advisory references withdrawn
195 Aldicarb 116-06-3 27 19940101 Jan 1,1994 III.A. Message revised to include contact's name and number
196 Aldicarb 116-06-3 28 19950801 Aug 1,1995 II.D.2. EPA's RfD/RfC and CRAVE workgroups were discontinued in May 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS reveiw. The IRIS Pilot Program replaced the workgroup functions beginning in September, 1995.
197 Aldicarb 116-06-3 29 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or befroe April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
198 Aldicarb 116-06-3 30 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
199 Aldicarb sulfone 1646-88-4 1 19880926 Sep 26,1988 I.A. Oral RfD summary on-line
200 Aldicarb sulfone 1646-88-4 2 19890201 Feb 1,1989 I.A.7. Secondary contact's phone number corrected
201 Aldicarb sulfone 1646-88-4 3 19890801 Aug 1,1989 I.A. Citations clarified
202 Aldicarb sulfone 1646-88-4 4 19890801 Aug 1,1989 VI. Bibliography on-line
203 Aldicarb sulfone 1646-88-4 5 19900701 Jul 1,1990 I.A. Withdrawn; new RfD verified (in preparation)
204 Aldicarb sulfone 1646-88-4 6 19900701 Jul 1,1990 VI. Bibliography withdrawn
205 Aldicarb sulfone 1646-88-4 7 19900901 Sep 1,1990 I.A. Oral RfD summary replaced; RfD changed
206 Aldicarb sulfone 1646-88-4 8 19900901 Sep 1,1990 VI. Bibliography replaced
207 Aldicarb sulfone 1646-88-4 9 19900501 May 1,1990 I.A. Oral RfD withdrawn pending additional review
208 Aldicarb sulfone 1646-88-4 10 19910501 May 1,1991 VI. Bibliography withdrawn
209 Aldicarb sulfone 1646-88-4 11 19920101 Jan 1,1992 IV. Regulatory Action section on-line
210 Aldicarb sulfone 1646-88-4 12 19921001 Oct 1,1992 I.A. Work group review date added
211 Aldicarb sulfone 1646-88-4 13 19930401 Apr 1,1993 I.A. Oral RfD references replaced
212 Aldicarb sulfone 1646-88-4 14 19931101 Nov 1,1993 I.A. Oral RfD summary replaced; new RfD
213 Aldicarb sulfone 1646-88-4 15 19931101 Nov 1,1993 VI.A. Oral RfD references replaced
214 Aldicarb sulfone 1646-88-4 16 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
215 Aldicarb sulfone 1646-88-4 17 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
216 Aldrin 309-00-2 1 19870930 Sep 30,1987 II. Carcinogenicity section added
217 Aldrin 309-00-2 2 19880301 Mar 1,1988 II.B.4 Confidence statement revised
218 Aldrin 309-00-2 3 19881201 Dec 1,1988 II.B.4. Corrected slope factor in text
219 Aldrin 309-00-2 4 19890901 Sep 1,1989 II.A.2. Dirtaglia reference changed to Ditraglia et al.
220 Aldrin 309-00-2 5 19890901 Sep 1,1989 II.A.3. Deichmann reference changed to Deichmann et al.
221 Aldrin 309-00-2 6 19890901 Sep 1,1989 II.B.3. Body weight for mice corrected to kg
222 Aldrin 309-00-2 7 19890901 Sep 1,1989 VI. Bibliography on-line
223 Aldrin 309-00-2 8 19910101 Jan 1,1991 II. Text edited
224 Aldrin 309-00-2 9 19910101 Jan 1,1991 II.C.1 Inhalation slope factor removed (global change)
225 Aldrin 309-00-2 10 19920101 Jan 1,1992 I.A.7. Secondary contact changed
226 Aldrin 309-00-2 11 19920101 Jan 1,1992 IV. Regulatory actions updated
227 Aldrin 309-00-2 12 19930701 Jul 1,1993 II.D.3. Secondary contact's phone number changed
228 Aldrin 309-00-2 13 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementay data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Praogram Offices for this information.
229 Aldrin 309-00-2 14 20190515 May 15,2019 Pesticide Marked this chemical as a pesticide. %5BSR%5D
230 Aldrin 309-00-2 15 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
231 Ally 74223-64-6 1 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
232 Allyl alcohol 107-18-6 1 19870930 Sep 30,1987 V. Supplementary Dta section added
233 Allyl alcohol 107-18-6 2 19880301 Mar 1,1988 I.A.1. Dose conversion clarified
234 Allyl alcohol 107-18-6 3 19880301 Mar 1,1988 I.A.2. Text deleted
235 Allyl alcohol 107-18-6 4 19880301 Mar 1,1988 I.A.4. Text clarified
236 Allyl alcohol 107-18-6 5 19880301 Mar 1,1988 I.A.5. Confidence levels revised
237 Allyl alcohol 107-18-6 6 19890801 Aug 1,1989 I.A.4. Citations clarified
238 Allyl alcohol 107-18-6 7 19890801 Aug 1,1989 VI. Bibliography on-line
239 Allyl alcohol 107-18-6 8 19920101 Jan 1,1992 I.A.7. Primary contact changed
240 Allyl alcohol 107-18-6 9 19920101 Jan 1,1992 IV. Regulatory action updated
241 Allyl alcohol 107-18-6 10 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS useres were directed to the appropriate EPA Program Offices for this information.
242 Allyl alcohol 107-18-6 11 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
243 Allyl chloride 107-05-1 1 19900901 Sep 1,1990 II. Carcinogen assessment on-line
244 Allyl chloride 107-05-1 2 19900901 Sep 1,1990 VI. Bibliography on-line
245 Allyl chloride 107-05-1 3 19910101 Jan 1,1991 I.B. Inhalation RfC now under review
246 Allyl chloride 107-05-1 4 19910801 Aug 1,1991 VI.C. Eder et al. 1980 reference volume corrected
247 Allyl chloride 107-05-1 5 19911201 Dec 1,1991 I.B. Inhalation RfC on-line
248 Allyl chloride 107-05-1 6 19911201 Dec 1,1991 VI.B. Inhalation RfC references added
249 Allyl chloride 107-05-1 7 19920101 Jan 1,1992 IV. Regulatory Action section on-line
250 Allyl chloride 107-05-1 8 19950501 May 1,1995 I.B. Principal study author name corrected
251 Allyl chloride 107-05-1 9 19950501 May 1,1995 VI.B. Author name corrected
252 Allyl chloride 107-05-1 10 19970401 Apr 1,1997 III., IV., V. Drinking Water Health advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
253 Allyl chloride 107-05-1 11 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
254 Aluminum phosphide 20859-73-8 1 19880301 Mar 1,1988 I.A.5. Confidence levels revised
255 Aluminum phosphide 20859-73-8 2 19880301 Mar 1,1988 I.A.6. Documentation revised
256 Aluminum phosphide 20859-73-8 3 19890801 Aug 1,1989 VI. Bibliography on-line
257 Aluminum phosphide 20859-73-8 4 19920101 Jan 1,1992 I.A.7. Primary contact changed
258 Aluminum phosphide 20859-73-8 5 19920101 Jan 1,1992 IV. Regulatory actions updated
259 Aluminum phosphide 20859-73-8 6 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
260 Aluminum phosphide 20859-73-8 8 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
261 Amdro 67485-29-4 1 19891101 Nov 1,1989 VI. Bibliography on-line
262 Amdro 67485-29-4 2 19920101 Jan 1,1992 IV. Regulatory Action section on-line
263 Amdro 67485-29-4 3 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were direcetd to the appropriate EPA Program Office for this information.
264 Amdro 67485-29-4 4 20160715 Jul 15,2016 Archived Assessment IRIS working with OPP agreed to mark this pesticide chemical archived.
265 Amdro 67485-29-4 5 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
266 Ametryn 834-12-8 1 19880301 Mar 1,1988 I.A.4. Text clarified
267 Ametryn 834-12-8 2 19891101 Nov 1,1989 I.A.4. Species corrected in study 4
268 Ametryn 834-12-8 3 19891101 Nov 1,1989 VI. Bibliography on-line
269 Ametryn 834-12-8 4 19901001 Oct 1,1990 III.A. Health Advisory on-line
270 Ametryn 834-12-8 5 19901001 Oct 1,1990 VI.D. Health Advisory references added
271 Ametryn 834-12-8 6 19920101 Jan 1,1992 IV. Regulatory Action section on-line
272 Ametryn 834-12-8 7 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
273 Ametryn 834-12-8 8 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
274 4-Aminopyridine 504-24-5 1 19891201 Dec 1,1989 II. Carcinogen summary on-line
275 4-Aminopyridine 504-24-5 2 19891201 Dec 1,1989 VI. Bibliography on-line
276 4-Aminopyridine 504-24-5 3 19911201 Dec 1,1991 II.A.1. Basis statement replaced
277 4-Aminopyridine 504-24-5 4 19911201 Dec 1,1991 II.A.4. Text replaced
278 4-Aminopyridine 504-24-5 5 19911201 Dec 1,1991 II.D.2. Review date of 07/25/1991 added
279 4-Aminopyridine 504-24-5 6 19920101 Jan 1,1992 IV. Regulatory Action section on-line
280 4-Aminopyridine 504-24-5 7 19930701 Jul 1,1993 II.D.1. Source document year corrected
281 4-Aminopyridine 504-24-5 8 19950801 Aug 1,1995 II.D.2. EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS review. The IRIS Pilot Program replaced the workgroup functions beginning in September, 1995.
282 4-Aminopyridine 504-24-5 9 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory ACtions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
283 4-Aminopyridine 504-24-5 10 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
284 Amitraz 33089-61-1 1 19880822 Aug 22,1988 I.A. Oral RfD summary on-line
285 Amitraz 33089-61-1 2 19881201 Dec 1,1988 I.A.4. Core grades corrected
286 Amitraz 33089-61-1 3 19891001 Oct 1,1989 VI. Bibliography on-line
287 Amitraz 33089-61-1 4 19920101 Jan 1,1992 IV. Regulatory Action section on-line
288 Amitraz 33089-61-1 5 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EP Program Offices for this information.
289 Amitraz 33089-61-1 6 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
290 Ammonia 7664-41-7 1 19910501 May 1,1991 I.B. Inhalation RfC summary on-line
291 Ammonia 7664-41-7 2 19910501 May 1,1991 VI. Bibliography on-line
292 Ammonia 7664-41-7 3 19920101 Jan 1,1992 IV. Regulatory Action section on-line
293 Ammonia 7664-41-7 4 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this inforamation.
294 Ammonia 7664-41-7 5 20160920 Sep 20,2016 I.B. Update to the noncancer inhalation RfC key values.
295 Ammonia 7664-41-7 6 20180628 Jun 28,2018 IRIS Summary Renamed the IRIS Summary to Executive summary to match the attachment.
296 Ammonia 7664-41-7 7 20200714 Jul 14,2020 Related Topics Added Chemicals Dashboard link
297 Ammonium acetate 631-61-8 1 19910301 Mar 1,1991 II. Carcinogenicity assessment on-line
298 Ammonium acetate 631-61-8 2 19910301 Mar 1,1991 VI. Bibliography on-line
299 Ammonium acetate 631-61-8 3 19920101 Jan 1,1992 IV. Regulatory Action section on-line
300 Ammonium acetate 631-61-8 4 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. Iris users were directed to the appropriate EPA Program Offices for this information.
301 Ammonium acetate 631-61-8 5 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
302 Ammonium methacrylate 16325-47-6 1 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
303 Ammonium sulfamate 7773-06-0 1 19880301 Mar 1,1988 I.A.1. Critical effect identified, LOAEL specified
304 Ammonium sulfamate 7773-06-0 2 19880301 Mar 1,1988 I.A.2. Principal study citation corrected
305 Ammonium sulfamate 7773-06-0 3 19880301 Mar 1,1988 I.A.2. Text revised
306 Ammonium sulfamate 7773-06-0 4 19881201 Dec 1,1988 I.A. Withdrawn; new RfD verified (in preparation)
307 Ammonium sulfamate 7773-06-0 5 19890101 Jan 1,1989 I.A. Oral RfD summary replaced; RfD changed
308 Ammonium sulfamate 7773-06-0 6 19910301 Mar 1,1991 I.A.4. Citations added
309 Ammonium sulfamate 7773-06-0 7 19910301 Mar 1,1991 III.A. Health Advisory on-line
310 Ammonium sulfamate 7773-06-0 8 19910301 Mar 1,1991 VI. Bibliography on-line
311 Ammonium sulfamate 7773-06-0 9 19910601 Jun 1,1991 III.A.4. 70-kg 'child' corrected to 70-kg adult in assumptions
312 Ammonium sulfamate 7773-06-0 10 19920101 Jan 1,1992 IV. Regulatory actions updated
313 Ammonium sulfamate 7773-06-0 11 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program offices for this information.
314 Ammonium sulfamate 7773-06-0 12 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
315 Aniline 62-53-3 1 19880907 Sep 7,1988 II. Carcinogen summary on-line
316 Aniline 62-53-3 2 19890401 Apr 1,1989 V. Supplementary data on-line
317 Aniline 62-53-3 3 19890601 Jun 1,1989 II.D.2. Work group review date added
318 Aniline 62-53-3 4 19890801 Aug 1,1989 VI. Bibliography on-line
319 Aniline 62-53-3 5 19901001 Oct 1,1990 I.B. Inhalation RfC now under review
320 Aniline 62-53-3 6 19901101 Nov 1,1990 I.B. Inhalation RfC summary on-line
321 Aniline 62-53-3 7 19901101 Nov 1,1990 VI.B. Inhalation RfC references added
322 Aniline 62-53-3 8 19911101 Nov 1,1991 I.B.6. Source Doc. & Other EPA Documentation corrected
323 Aniline 62-53-3 9 19920101 Jan 1,1992 IV. Regulatory Action section on-line
324 Aniline 62-53-3 10 19931201 Dec 1,1993 I.B.1. Critical effect clarified in study 1
325 Aniline 62-53-3 11 19940201 Feb 1,1994 II.D.3. Secondary contact's phone number changed
326 Aniline 62-53-3 12 19950801 Aug 1,1995 II.D.2. EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS review. The IRIS Pilot Program replaced the workgroup functions beginning in September, 1995.
327 Aniline 62-53-3 13 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementarry Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
328 Aniline 62-53-3 15 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
329 ortho-Anisidine 90-04-0 1 19910901 Sep 1,1991 I.B. Inhalation RfC now under review
330 ortho-Anisidine 90-04-0 2 19911001 Oct 1,1991 I.B. Inhalation RfC message on-line
331 ortho-Anisidine 90-04-0 3 19911001 Oct 1,1991 VI. Bibliography on-line
332 ortho-Anisidine 90-04-0 4 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were direcetd to the appropriate EPA Program Offices for this information.
333 ortho-Anisidine 90-04-0 5 20181219 Dec 19,2018 Archived Chemical IRIS Program requested that we archive assessments with no values.
334 ortho-Anisidine 90-04-0 6 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
335 Anthracene 120-12-7 1 19900901 Sep 1,1990 I.A. Oral RfD summary on-line
336 Anthracene 120-12-7 2 19900901 Sep 1,1990 VI. Bibliography on-line
337 Anthracene 120-12-7 3 19910101 Jan 1,1991 II. Carcinogen assessment on-line
338 Anthracene 120-12-7 4 19910101 Jan 1,1991 VI.C. Carcinogen assessment references added
339 Anthracene 120-12-7 5 19910701 Jul 1,1991 I.A.7. Primary and secondary contacts changed
340 Anthracene 120-12-7 6 19920101 Jan 1,1992 IV. Regulatory Action section on-line
341 Anthracene 120-12-7 7 19930701 Jul 1,1993 I.A.6. Source Document and Other EPA documentation clarified
342 Anthracene 120-12-7 8 19940901 Sep 1,1994 I.B. Inhalation RfD now under review
343 Anthracene 120-12-7 9 19950801 Aug 1,1995 I.B. EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS reveiw. The IRIS Pilot Program replaced the workgroup functions beginning in September, 1995.
344 Anthracene 120-12-7 10 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplmentary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
345 Anthracene 120-12-7 12 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
346 Antimony 7440-36-0 1 19890801 Aug 1,1989 I.A. Gross et al., (1955) citation clarified
347 Antimony 7440-36-0 2 19890801 Aug 1,1989 VI. Bibliography on-line
348 Antimony 7440-36-0 3 19910201 Feb 1,1991 I.A.1. Conversion factor revised
349 Antimony 7440-36-0 4 19910201 Feb 1,1991 I.A.2. Text added
350 Antimony 7440-36-0 5 19910201 Feb 1,1991 I.A.4. Paragraph 2 added
351 Antimony 7440-36-0 6 19910201 Feb 1,1991 VI.A. Dunn, 1928 and Monier-Williams, 1934 added
352 Antimony 7440-36-0 7 19920101 Jan 1,1992 I.A.7. Primary contact changed
353 Antimony 7440-36-0 8 19920101 Jan 1,1992 IV. Regulatory actions updated
354 Antimony 7440-36-0 9 19970401 Apr 1,1997 III>, IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directeed to the appropriate EPA Program Offices for this information.
355 Antimony 7440-36-0 10 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
356 Antimony trioxide 1309-64-4 1 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
357 Apollo 74115-24-5 1 19880301 Mar 1,1988 I.A.3. Text revised
358 Apollo 74115-24-5 2 19880301 Mar 1,1988 I.A.4. Data gaps revised
359 Apollo 74115-24-5 3 19880301 Mar 1,1988 I.A.4. Study description added
360 Apollo 74115-24-5 4 19880301 Mar 1,1988 I.A.4. Data added to 'Other Data Reviewed'
361 Apollo 74115-24-5 5 19880301 Mar 1,1988 I.A.5. Confidence levels revised
362 Apollo 74115-24-5 6 19880301 Mar 1,1988 I.A.6. Dates corrected
363 Apollo 74115-24-5 7 19891101 Nov 1,1989 I.A. Principal study year corrected
364 Apollo 74115-24-5 8 19891101 Nov 1,1989 VI. Bibliography on-line
365 Apollo 74115-24-5 9 19900301 Mar 1,1990 II. Carcinogen assessment now under review
366 Apollo 74115-24-5 10 19910601 Jun 1,1991 II. Carcinogenicity assessment on-line
367 Apollo 74115-24-5 11 19910601 Jun 1,1991 VI.C. Carcinogenicity references added
368 Apollo 74115-24-5 12 19931001 Oct 1,1993 II.D.3. Primary contact changed; secondary's phone no. changed.
369 Apollo 74115-24-5 13 19950801 Aug 1,1995 I.A.6. EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS review. The IRIS Pilot Program replaced the workgroup functions beginning in September, 1995.
370 Apollo 74115-24-5 14 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
371 Apollo 74115-24-5 15 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
372 Aramite 140-57-8 1 19910601 Jun 1,1991 II. Carcinogenicity assessment on-line
373 Aramite 140-57-8 2 19910601 Jun 1,1991 VI. Bibliography on-line
374 Aramite 140-57-8 3 19920101 Jan 1,1992 IV. Regulatory Action section on-line
375 Aramite 140-57-8 4 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
376 Aramite 140-57-8 5 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
377 Aroclor 1016 12674-11-2 1 19910801 Aug 1,1991 I.A. Oral RfD now under review
378 Aroclor 1016 12674-11-2 2 19920801 Aug 1,1992 I.A. Work group review dates added
379 Aroclor 1016 12674-11-2 3 19921001 Oct 1,1992 I.A. Work group review date added
380 Aroclor 1016 12674-11-2 4 19921201 Dec 1,1992 I.A. Work group reveiw dates added
381 Aroclor 1016 12674-11-2 5 19930101 Jan 1,1993 I.A. Oral RfD assessment on-line
382 Aroclor 1016 12674-11-2 6 19930101 Jan 1,1993 VI.A. Oral RfD references on-line
383 Aroclor 1016 12674-11-2 7 19930201 Feb 1,1993 VI.A. Oral RfD references corrected
384 Aroclor 1016 12674-11-2 8 19930301 Mar 1,1993 I.A.6. Work group review date added
385 Aroclor 1016 12674-11-2 9 19930901 Sep 1,1993 I.A. Oral RfD noted as going to be externally peer reviewed
386 Aroclor 1016 12674-11-2 10 19931101 Nov 1,1993 I.A. Note revised
387 Aroclor 1016 12674-11-2 11 19940501 May 1,1994 I.A. Peer review note removed; peer review May 24-25
388 Aroclor 1016 12674-11-2 12 19950801 Aug 1,1995 I.A.6., I.A. EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS review. The IRIS Pilot Program replaced the workgroup functions beginning in September, 1995.
389 Aroclor 1016 12674-11-2 13 19961101 Nov 1,1996 I.A.7. Primary contact's office changed
390 Aroclor 1016 12674-11-2 14 19970401 Apr 1,1997 III., IV., V. Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
391 Aroclor 1016 12674-11-2 15 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
392 Aroclor 1248 12672-29-6 1 19920901 Sep 1,1992 I.A. Oral RfD now under review
393 Aroclor 1248 12672-29-6 2 19921201 Dec 1,1992 I.A. Work group review date added
394 Aroclor 1248 12672-29-6 3 19930701 Jul 1,1993 I.A. Work group review date added
395 Aroclor 1248 12672-29-6 4 19930801 Aug 1,1993 I.A. Work group review date added
396 Aroclor 1248 12672-29-6 5 19940401 Apr 1,1994 I.A. Oral RfD message on-line
397 Aroclor 1248 12672-29-6 6 19940401 Apr 1,1994 VI.A. Oral RfD references on-line
398 Aroclor 1248 12672-29-6 7 19961101 Nov 1,1996 I.A. Contact's office changed
399 Aroclor 1248 12672-29-6 8 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
400 Aroclor 1248 12672-29-6 9 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
401 Aroclor 1254 11097-69-1 1 19930701 Jul 1,1993 I.A. Oral RfD now under review
402 Aroclor 1254 11097-69-1 2 19930901 Sep 1,1993 A11. Monor edit
403 Aroclor 1254 11097-69-1 3 19940301 Mar 1,1994 I.A. Work group review date added
404 Aroclor 1254 11097-69-1 4 19941001 Oct 1,1994 I.A. Oral RfD summary on-line
405 Aroclor 1254 11097-69-1 5 19941001 Oct 1,1994 VI.A. Oral RfD references on-line
406 Aroclor 1254 11097-69-1 6 19961101 Nov 1,1996 I.A.7. Primary contact's office changed
407 Aroclor 1254 11097-69-1 7 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
408 Aroclor 1254 11097-69-1 8 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
409 Arsenic, Inorganic 7440-38-2 1 19880630 Jun 30,1988 II.B. Revised last paragraph
410 Arsenic, Inorganic 7440-38-2 2 19880630 Jun 30,1988 II.C.1. Inhalation slope factor changed
411 Arsenic, Inorganic 7440-38-2 3 19880630 Jun 30,1988 II.C.3. Paragraph 2 added
412 Arsenic, Inorganic 7440-38-2 4 19880907 Sep 7,1988 II.B. Major text changes
413 Arsenic, Inorganic 7440-38-2 5 19881201 Dec 1,1988 II.A.2 Mabuchi et al., citation year corrected
414 Arsenic, Inorganic 7440-38-2 6 19881201 Dec 1,1988 II.A.3. Pershagen et al., citation year corrected
415 Arsenic, Inorganic 7440-38-2 7 19890901 Sep 1,1989 II.C.2. Citations added to Anacondor smelter
416 Arsenic, Inorganic 7440-38-2 8 19890901 Sep 1,1989 VI. Bibliography on-line
417 Arsenic, Inorganic 7440-38-2 9 19900601 Jun 1,1990 II.A.2. 2nd and 3rd paragraph - Text revised
418 Arsenic, Inorganic 7440-38-2 10 19900601 Jun 1,1990 II.A.4. Text corrected
419 Arsenic, Inorganic 7440-38-2 11 19900601 Jun 1,1990 II.C.1. Inhalation slope factor removed (format change)
420 Arsenic, Inorganic 7440-38-2 12 19900601 Jun 1,1990 IV.F.1. EPA contact changed
421 Arsenic, Inorganic 7440-38-2 13 19900601 Jun 1,1990 VI.C. References added
422 Arsenic, Inorganic 7440-38-2 14 19901201 Dec 1,1990 II.B. Changed slope factor to "unit risk", 2nd paragraph, 1st sentence
423 Arsenic, Inorganic 7440-38-2 15 19910201 Feb 1,1991 II.C.3. Text edited
424 Arsenic, Inorganic 7440-38-2 16 19910901 Sep 1,1991 I.A. Oral RfD summary now on-line
425 Arsenic, Inorganic 7440-38-2 17 19910901 Sep 1,1991 I.A. Oral RfD bibliography added
426 Arsenic, Inorganic 7440-38-2 18 19911001 Oct 1,1991 I.A.1. Conversion factor text clarified
427 Arsenic, Inorganic 7440-38-2 19 19911001 Oct 1,1991 IV.B.1. MCLG noted as pending change
428 Arsenic, Inorganic 7440-38-2 20 19920101 Jan 1,1992 IV. Regulatory actions updated
429 Arsenic, Inorganic 7440-38-2 21 19920801 Aug 1,1992 II. Note added to indicate text in oral quant. estimate
430 Arsenic, Inorganic 7440-38-2 22 19921001 Oct 1,1992 VI.C. Missing reference added to bibliography
431 Arsenic, Inorganic 7440-38-2 23 19930201 Feb 1,1993 I.A.4. Citations added to second paragraph
432 Arsenic, Inorganic 7440-38-2 24 19930201 Feb 1,1993 VI.A. References added to bibliography
433 Arsenic, Inorganic 7440-38-2 25 19930301 Mar 1,1993 VI.A. Corrections to references
434 Arsenic, Inorganic 7440-38-2 26 19940301 Mar 1,1994 II.D.2. Work group review date added
435 Arsenic, Inorganic 7440-38-2 27 19940601 Jun 1,1994 II. Carcinogen assessment noted as pending change
436 Arsenic, Inorganic 7440-38-2 28 19950101 Jan 1,1995 II. Pending change note revised
437 Arsenic, Inorganic 7440-38-2 29 19950101 Jan 1,1995 II.B. Dates and document no. added to oral quant. estimate
438 Arsenic, Inorganic 7440-38-2 30 19950601 Jun 1,1995 II. Carcinogenicity assessment replaced
439 Arsenic, Inorganic 7440-38-2 31 19950601 Jun 1,1995 VI.C. Carcinogenicity references replaced
440 Arsenic, Inorganic 7440-38-2 32 19950701 Jul 1,1995 II.D.1 Documentation year corrected; review statement revised
441 Arsenic, Inorganic 7440-38-2 33 19950701 Jul 1,1995 VI.C. U.S. EPA, 1994 corrected to 1993
442 Arsenic, Inorganic 7440-38-2 34 19950801 Aug 1,1995 II.D.2. EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS review. The IRIS Pilot Program replaced the workgroup functions beginning in September, 1995.
443 Arsenic, Inorganic 7440-38-2 35 19970401 Apr 1,1997 III.,IV.,V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
444 Arsenic, Inorganic 7440-38-2 36 19980410 Apr 10,1998 II.B.3. Added discussion on expert panel workshop
445 Arsenic, Inorganic 7440-38-2 37 20000211 Feb 11,2000 II.C.2. Corrected alignment of unit risks in table with corresponding studies
446 Arsenic, Inorganic 7440-38-2 38 20200714 Jul 14,2020 Related Topics Added Chemicals Dashboard link
447 Arsine 7784-42-1 1 19930301 Mar 1,1993 I.B. Inhalation RfC now under review
448 Arsine 7784-42-1 2 19940301 Mar 1,1994 I.B. Inhalation RfC on-line
449 Arsine 7784-42-1 3 19940301 Mar 1,1994 VI.B. Inhalation RfC references on-line
450 Arsine 7784-42-1 4 19970401 Apr 1,1997 III.,IV.,V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
451 Arsine 7784-42-1 5 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
452 Asbestos 1332-21-4 1 19880926 Sep 26,1988 II. Carcinogen summary on-line
453 Asbestos 1332-21-4 2 19890501 May 1,1989 II. Carcinogen summary noted as pending change
454 Asbestos 1332-21-4 3 19891201 Dec 1,1989 VI. Bibliography on-line
455 Asbestos 1332-21-4 4 19910301 Mar 1,1991 II.A.1. Text revised
456 Asbestos 1332-21-4 5 19910701 Jul 1,1991 II.C.3 Last paragraph units changed from ug/cu.m to fibers/ml
457 Asbestos 1332-21-4 6 19920101 Jan 1,1992 IV. Regulatory Action section on-line
458 Asbestos 1332-21-4 7 19930701 Jul 1,1993 II.D.1. EPA Documentation clarified
459 Asbestos 1332-21-4 8 19930701 Jul 1,1993 VI.C. References alphabetized correctly
460 Asbestos 1332-21-4 9 19950801 Aug 1,1995 II. EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS review. The IRIS Pilot Program replaced the workgroup functions beginning in September, 1995.
461 Asbestos 1332-21-4 10 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
462 Asbestos 1332-21-4 11 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
463 Assure 76578-14-8 1 19880926 Sep 26,1988 I.A. Oral RfD summary on-line
464 Assure 76578-14-8 2 19891001 Oct 1,1989 VI. Bibliography on-line
465 Assure 76578-14-8 3 19910601 Jun 1,1991 II. Carcinogenicity assessment on-line
466 Assure 76578-14-8 4 19910601 Jun 1,1991 VI.C. Carcinogenicity references added
467 Assure 76578-14-8 5 19910701 Jul 1,1991 II.D.2. Work group review date corrected
468 Assure 76578-14-8 6 19931001 Oct 1,1993 II.D.3. Primary contact changed; secondary's phone no. changed
469 Assure 76578-14-8 7 19950801 Aug 1,1995 II.D.2. EPA's RfD/RfC and CRAVE workgropups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS review. The IRIS pilot Program replaced the workgroup functions beginning in September, 1995.
470 Assure 76578-14-8 8 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
471 Assure 76578-14-8 9 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
472 Asulam 3337-71-1 1 19891101 Nov 1,1989 VI. Bibliography on-line
473 Asulam 3337-71-1 2 19920101 Jan 1,1992 IV. Regulatory action section on-line
474 Asulam 3337-71-1 3 19950101 Jan 1,1995 I.A. Oral RfD noted as pending change
475 Asulam 3337-71-1 4 19950101 Jan 1,1995 I.A.6. Work group reveiw date added
476 Asulam 3337-71-1 5 19950801 Aug 1,1995 I.A.,I.A.6. EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reveiws that were not completed by September 1995 were taken out of IRIS review. The IRIS Pilot Program replaced the workgroup functions beginning in September, 1995.
477 Asulam 3337-71-1 6 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
478 Asulam 3337-71-1 7 20160715 Jul 15,2016 Archived Chemical IRIS working with OPP agreed to mark this pesticide chemical archived.
479 Asulam 3337-71-1 8 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
480 Atrazine 1912-24-9 1 19880301 Mar 1,1988 I.A.5. Confidence levels revised
481 Atrazine 1912-24-9 2 19880822 Aug 22,1988 I.A. Withdrawn; new oral RfD in preparation
482 Atrazine 1912-24-9 3 19880907 Sep 7,1988 I.A. Revised oral RfD summary added
483 Atrazine 1912-24-9 4 19891001 Oct 1,1989 VI. Bibliography on-line
484 Atrazine 1912-24-9 5 19900301 Mar 1,1990 I.A. Withdrawn; new oral RfD in preparation
485 Atrazine 1912-24-9 6 19900301 Mar 1,1990 VI.A. Oral RfD references withdrawn
486 Atrazine 1912-24-9 7 19900501 May 1,1990 I.A. Oral RfD summary replaced; RfD unchanged
487 Atrazine 1912-24-9 8 19900501 May 1,1990 VI.A. Oral RfD references replaced
488 Atrazine 1912-24-9 9 19910101 Jan 1,1991 I.A. Text edited
489 Atrazine 1912-24-9 10 19910101 Jan 1,1991 II. Carcinogen assessment now under review
490 Atrazine 1912-24-9 11 19920101 Jan 1,1992 IV. Regulatory Action section on-line
491 Atrazine 1912-24-9 12 19921201 Dec 1,1992 I.A. Oral RfD summary noted as pending change
492 Atrazine 1912-24-9 13 19921201 Dec 1,1992 I.A.6. Work group review date added
493 Atrazine 1912-24-9 14 19930101 Jan 1,1993 I.A. Withdrawn; new oral RfD in preparation
494 Atrazine 1912-24-9 15 19930101 Jan 1,1993 I.A. Work group review date added
495 Atrazine 1912-24-9 16 19930101 Jan 1,1993 VI.A. Oral RfD references withdrawn
496 Atrazine 1912-24-9 17 19931001 Oct 1,1993 I.A. Oral RfD summary replaced; RfD changed
497 Atrazine 1912-24-9 18 19931001 Oct 1,1993 VI.A. Oral RfD references replaced
498 Atrazine 1912-24-9 19 19950801 Aug 1,1995 II. EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS review. The IRIS Pilot Program replaced the workgroup functions beginning ing September, 1995.
499 Atrazine 1912-24-9 20 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
500 Atrazine 1912-24-9 21 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
501 Avermectin B1 65195-55-3 1 19890701 Jul 1,1989 I.A. Oral RfD summary on-line
502 Avermectin B1 65195-55-3 2 19890701 Jul 1,1989 VI. Bibliography on-line
503 Avermectin B1 65195-55-3 3 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Acions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
504 Avermectin B1 65195-55-3 4 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
505 Azobenzene 103-33-3 1 19880907 Sep 7,1988 II. Carcinogen summary on-line
506 Azobenzene 103-33-3 2 19890801 Aug 1,1989 VI. Bibliography on-line
507 Azobenzene 103-33-3 3 19910101 Jan 1,1991 II. Text edited
508 Azobenzene 103-33-3 4 19910101 Jan 1,1991 II.C.1. Inhalation slope factor removed (global change)
509 Azobenzene 103-33-3 5 19930701 Jul 1,1993 II.D.3. Secondary contact's phone number changed
510 Azobenzene 103-33-3 6 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisoreis, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information
511 Azobenzene 103-33-3 7 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
512 Barium and Compounds 7440-39-3 1 19870930 Sep 30,1987 IV. Regulatory Action section added
513 Barium and Compounds 7440-39-3 2 19880301 Mar 1,1988 I.A.1. Dose conversion clarified
514 Barium and Compounds 7440-39-3 3 19880301 Mar 1,1988 I.A.3. Text changed
515 Barium and Compounds 7440-39-3 4 19880301 Mar 1,1988 I.A.7. Secondary contact changed
516 Barium and Compounds 7440-39-3 5 19880630 Jun 30,1988 I.A.7. Contacts switched
517 Barium and Compounds 7440-39-3 6 19890801 Aug 1,1989 VI. Bibliography on-line
518 Barium and Compounds 7440-39-3 7 19900601 Jun 1,1990 IV.F.1. EPA contact changed
519 Barium and Compounds 7440-39-3 8 19900701 Jul 1,1990 I.A. Withdrawn; new RfD verified (in preparation)
520 Barium and Compounds 7440-39-3 9 19900701 Jul 1,1990 VI. Bibliography withdrawn
521 Barium and Compounds 7440-39-3 10 19900801 Aug 1,1990 I.A. Oral RfD summary replaced; RfD changed
522 Barium and Compounds 7440-39-3 11 19900801 Aug 1,1990 VI. Bibliography replaced
523 Barium and Compounds 7440-39-3 12 19901201 Dec 1,1990 I.B. Inhalation RfC now under review
524 Barium and Compounds 7440-39-3 13 19920101 Jan 1,1992 IV. Regulatory actions updated
525 Barium and Compounds 7440-39-3 14 19950801 Aug 1,1995 I.B. EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS review. The IRIS Pilot Program replaced the workgroup functions beginning in September, 1995.
526 Barium and Compounds 7440-39-3 15 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
527 Barium and Compounds 7440-39-3 16 19980330 Mar 30,1998 I.A. Oral RfD Assessment
528 Barium and Compounds 7440-39-3 17 19980330 Mar 30,1998 I.B. Inahalation RfC Assessment
529 Barium and Compounds 7440-39-3 18 19980330 Mar 30,1998 II. Carcinogenicity Assessment
530 Barium and Compounds 7440-39-3 19 19990121 Jan 21,1999 I.A. Minor revisions to RfD Assessment, revised critical effect
531 Barium and Compounds 7440-39-3 20 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
532 Barium cyanide 542-62-1 1 19880301 Mar 1,1988 I.A.2. Text revised paragraph 3
533 Barium cyanide 542-62-1 2 19890101 Jan 1,1989 I.A.1. LOAEL dose rate units corrected
534 Barium cyanide 542-62-1 3 19910301 Mar 1,1991 VI. Bibliography withdrawn
535 Barium cyanide 542-62-1 4 19891101 Nov 1,1989 VI. Bibliography on-line
536 Barium cyanide 542-62-1 5 19910301 Mar 1,1991 I.A. Oral RfD withdrawn pending additional review
537 Barium cyanide 542-62-1 6 19920101 Jan 1,1992 IV. Regulatory actions updated
538 Barium cyanide 542-62-1 7 19930801 Aug 1,1993 I.A. Oral RfD withdrawn pending addditional review
539 Barium cyanide 542-62-1 8 19930801 Aug 1,1993 I.A. EPA contact changed
540 Barium cyanide 542-62-1 9 19950801 Aug 1,1995 I.A. EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS review. The IRIS Pilot Program replaced the workgroup functions beginning in September, 1995.
541 Barium cyanide 542-62-1 10 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
542 Barium cyanide 542-62-1 11 20181219 Dec 19,2018 Archived Chemical IRIS Program requested that we archive assessments with no values.
543 Barium cyanide 542-62-1 12 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
544 Baygon 114-26-1 1 19870331 Mar 31,1987 I.A.6. Documentation corrected
545 Baygon 114-26-1 2 19870331 Mar 31,1987 IV.A. Pesticide AI data added
546 Baygon 114-26-1 3 19891101 Nov 1,1989 VI. Bibliography on-line
547 Baygon 114-26-1 4 19901001 Oct 1,1990 III.A. Health Advisory on-line
548 Baygon 114-26-1 5 19901001 Oct 1,1990 VI.D. Health Advisory references added
549 Baygon 114-26-1 6 19920101 Jan 1,1992 IV. Regulatory action updated
550 Baygon 114-26-1 7 19920701 Jul 1,1992 I.A.4. Study 5 citation corrected
551 Baygon 114-26-1 8 19970401 Apr 1,1997 III., IV., V., VI.D. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS useres were directed to the appropriate EPA Program Offices for this information.
552 Baygon 114-26-1 9 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
553 Bayleton 43121-43-3 1 19880301 Mar 1,1988 I.A.1. Dose conversion clarified
554 Bayleton 43121-43-3 2 19880301 Mar 1,1988 I.A.4. Core grades added
555 Bayleton 43121-43-3 3 19891101 Nov 1,1989 VI. Bibliography on-line
556 Bayleton 43121-43-3 4 19920101 Jan 1,1992 IV. Regulatory action on-line
557 Bayleton 43121-43-3 5 19870401 Apr 1,1987 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS useres were directed to the appropriate EPA Program Offices for this information.
558 Bayleton 43121-43-3 6 20160715 Jul 15,2016 Archived Chemical IRIS working with OPP agreed to mark this pesticide chemical archived.
559 Bayleton 43121-43-3 7 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
560 Baythroid 68359-37-5 1 19891101 Nov 1,1989 VI. Bibliography on-line
561 Baythroid 68359-37-5 2 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
562 Baythroid 68359-37-5 3 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
563 Benefin 1861-40-1 1 20160715 Jul 15,2016 Archived Chemical IRIS working with OPP agreed to mark this pesticide chemical archived.
564 Benefin 1861-40-1 2 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
565 Benomyl 17804-35-2 1 19880301 Mar 1,1988 I.A.5. Confidence levels revised
566 Benomyl 17804-35-2 2 19890301 Mar 1,1989 I.A. Major text revisions
567 Benomyl 17804-35-2 3 19890701 Jul 1,1989 VI. Bibliography on-line
568 Benomyl 17804-35-2 4 19920101 Jan 1,1992 IV. Regulatory action updated
569 Benomyl 17804-35-2 5 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
570 Benomyl 17804-35-2 6 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
571 Bentazon (Basagran) 25057-89-0 1 19890401 Apr 1,1989 III. Health Advisory on-line
572 Bentazon (Basagran) 25057-89-0 2 19891101 Nov 1,1989 VI. Bibliography on-line
573 Bentazon (Basagran) 25057-89-0 3 19910501 May 1,1991 I.A. Oral RfD Summary noted as pending change
574 Bentazon (Basagran) 25057-89-0 4 19920101 Jan 1,1992 IV. Regulatory action section on-line
575 Bentazon (Basagran) 25057-89-0 5 19950101 Jan 1,1995 I.A.6. Workgroup review date added
576 Bentazon (Basagran) 25057-89-0 6 19950801 Aug 1,1995 I.A., I.A.6. EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRS review. The IRIS Pilot Program replaced the workgroup functions beginning in September, 1995.
577 Bentazon (Basagran) 25057-89-0 7 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
578 Bentazon (Basagran) 25057-89-0 8 19980302 Mar 2,1998 I.A., II., VI. New RfD, cancer assessment
579 Bentazon (Basagran) 25057-89-0 9 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
580 Benz[a]anthracene 56-55-3 1 19901201 Dec 1,1990 II. Carcinogen assessment on-line
581 Benz[a]anthracene 56-55-3 2 19901201 Dec 1,1990 VI. Bibliography on-line
582 Benz[a]anthracene 56-55-3 3 19920101 Jan 1,1992 IV. Regulatory Action section on-line
583 Benz[a]anthracene 56-55-3 4 19930901 Sep 1,1993 II. Carcinogenicity assessment noted as pending change
584 Benz[a]anthracene 56-55-3 5 19930901 Sep 1,1993 II.D.2. Work group review date added
585 Benz[a]anthracene 56-55-3 6 19931101 Nov 1,1993 II.D.2. Work group reveiw date added
586 Benz[a]anthracene 56-55-3 7 19940301 Mar 1,1994 II. Pending change note removed; no change
587 Benz[a]anthracene 56-55-3 8 19940301 Mar 1,1994 II.D.2. Work group review date added
588 Benz[a]anthracene 56-55-3 9 19940901 Sep 1,1994 I.B. Inhalation RfC now under review
589 Benz[a]anthracene 56-55-3 10 19950801 Aug 1,1995 I.B., II.D.2. EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS review. The IRIS Pilot Program replaced the workgroup functions beginning in September, 1995.
590 Benz[a]anthracene 56-55-3 11 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
591 Benz[a]anthracene 56-55-3 12 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
592 Benzaldehyde 100-52-7 1 19880907 Sep 7,1988 I.A. Oral RfD summary on-line
593 Benzaldehyde 100-52-7 2 19891201 Dec 1,1989 VI. Bibliography on-line
594 Benzaldehyde 100-52-7 3 19920101 Jan 1,1992 I.A.7. Secondary contact changed
595 Benzaldehyde 100-52-7 4 19920101 Jan 1,1992 IV. Regulatory Action section on-line
596 Benzaldehyde 100-52-7 5 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
597 Benzaldehyde 100-52-7 6 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
598 Benzene 71-43-2 1 19881201 Dec 1,1988 II.A.4. Anderson and Richardson citation year corrected
599 Benzene 71-43-2 2 19881201 Dec 1,1988 II.A.4. Kissling and Speck citation year corrected
600 Benzene 71-43-2 3 19890701 Jul 1,1989 I.B. Inhalation RfD now under review
601 Benzene 71-43-2 4 19900201 Feb 1,1990 II. Clarified citations
602 Benzene 71-43-2 5 19900201 Feb 1,1990 II.A.3. Corrected Maltoni, 1979 to Maltoni and Scarnato, 1979
603 Benzene 71-43-2 6 19900201 Feb 1,1990 II.A.3. Corrected Maltoni, 1983 to Maltoni et al., 1983
604 Benzene 71-43-2 7 19900201 Feb 1,1990 II.A.3. Corrected Synder et al., 1980 to 1981
605 Benzene 71-43-2 8 19900201 Feb 1,1990 VI. Bibliography on-line
606 Benzene 71-43-2 9 19900301 Mar 1,1990 VI.C. Clarify Maltoni et al., 1983 and NTP, 1986 references
607 Benzene 71-43-2 10 19900801 Aug 1,1990 III.A.10. Primary contact changed
608 Benzene 71-43-2 11 19900801 Aug 1,1990 IV.F.1. EPA contact changed
609 Benzene 71-43-2 12 19910101 Jan 1,1991 II. Text edited
610 Benzene 71-43-2 13 19910101 Jan 1,1991 II.C.1. Inhalation slope factor removed (global change)
611 Benzene 71-43-2 14 19920101 Jan 1,1992 IV. Regulatory actions updated
612 Benzene 71-43-2 15 19920401 Apr 1,1992 II.B.2. Text revised
613 Benzene 71-43-2 16 19940201 Feb 1,1994 II.D.3. Secondary contact's phone number changed
614 Benzene 71-43-2 17 19981016 Oct 16,1998 II., VI. Revised inhalation carcinogenicity section and references
615 Benzene 71-43-2 18 20000119 Jan 19,2000 II., VI. Revised oral carcinogenicity section and references
616 Benzene 71-43-2 19 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
617 Benzidine 92-87-5 1 19880301 Mar 1,1988 II.B.4. Confidence statement revised
618 Benzidine 92-87-5 2 19880301 Mar 1,1988 II.C.4. Confidence statement revised
619 Benzidine 92-87-5 3 19880301 Mar 1,1988 II.D.3. Contacts switched
620 Benzidine 92-87-5 4 19880907 Sep 7,1988 I.A. Oral RfD summary on-line
621 Benzidine 92-87-5 5 19890101 Jan 1,1989 I.A.1. LOAEL and RfD corrected
622 Benzidine 92-87-5 6 19890101 Jan 1,1989 I.A.2. Dose levels corrected
623 Benzidine 92-87-5 7 19900101 Jan 1,1990 I.A.2. Clarify text
624 Benzidine 92-87-5 8 19900101 Jan 1,1990 II.A.2. Corrected Zavon et al. (1973) to Zavon (1973)
625 Benzidine 92-87-5 9 19900101 Jan 1,1990 II.A.4. Corrected Parodi, 1983 to Parodi et al., 1983
626 Benzidine 92-87-5 10 19900101 Jan 1,1990 VI. Bibliography on-line
627 Benzidine 92-87-5 11 19910501 May 1,1991 I.B. Inhalation RfC now under review
628 Benzidine 92-87-5 12 19910701 Jul 1,1991 I.B. Inhalation RfC message on-line
629 Benzidine 92-87-5 13 19910701 Jul 1,1991 VI.B. Inhalation RfC references added
630 Benzidine 92-87-5 14 19920101 Jan 1,1992 I.A.7. Secondary contact changed
631 Benzidine 92-87-5 15 19920101 Jan 1,1992 IV. Regulatory actions updated
632 Benzidine 92-87-5 16 19930701 Jul 1,1993 II.D.1. Zavon, 1973 reference removed from EPA Documentation
633 Benzidine 92-87-5 17 19950201 Feb 1,1995 I.A.7. Secondary contact's name changed
634 Benzidine 92-87-5 18 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
635 Benzidine 92-87-5 19 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
636 Benzo[a]pyrene (BaP) 50-32-8 1 19890801 Aug 1,1989 VI. Bibliography on-line
637 Benzo[a]pyrene (BaP) 50-32-8 2 19920101 Jan 1,1992 II. Carcinogen assessment noted as pending change
638 Benzo[a]pyrene (BaP) 50-32-8 3 19920101 Jan 1,1992 IV. Regulatory actions updated
639 Benzo[a]pyrene (BaP) 50-32-8 4 19920401 Apr 1,1992 II. Summary revised oral quantitative section added
640 Benzo[a]pyrene (BaP) 50-32-8 5 19920401 Apr 1,1992 VI.C. Carcinogen assessment references revised
641 Benzo[a]pyrene (BaP) 50-32-8 6 19920501 May 1,1992 II.D.2. Work group review and verification date corrected
642 Benzo[a]pyrene (BaP) 50-32-8 7 19920701 Jul 1,1992 II. Text revised in Note
643 Benzo[a]pyrene (BaP) 50-32-8 8 19920701 Jul 1,1992 II.B. Range of slope factors corrected
644 Benzo[a]pyrene (BaP) 50-32-8 9 19920701 Jul 1,1992 II.B.1. Slope factor and risks corrected
645 Benzo[a]pyrene (BaP) 50-32-8 10 19920701 Jul 1,1992 II.B.2. Data table heading corrected
646 Benzo[a]pyrene (BaP) 50-32-8 11 19920701 Jul 1,1992 II.B.3. Slope factor corrected last paragraph
647 Benzo[a]pyrene (BaP) 50-32-8 12 19920701 Jul 1,1992 II.D.3. Secondary contact changed
648 Benzo[a]pyrene (BaP) 50-32-8 13 19930901 Sep 1,1993 II. Carcinogenicity assessment noted as pending change
649 Benzo[a]pyrene (BaP) 50-32-8 14 19930901 Sep 1,1993 II.D.2. Work group review date added
650 Benzo[a]pyrene (BaP) 50-32-8 15 19931201 Dec 1,1993 VI.C. Reference revised - U.S. EPA, 1991b
651 Benzo[a]pyrene (BaP) 50-32-8 16 19940201 Feb 1,1994 II.D.3. Primary contact's phone number changed
652 Benzo[a]pyrene (BaP) 50-32-8 17 19940301 Mar 1,1994 II.D.2. Work group review date added
653 Benzo[a]pyrene (BaP) 50-32-8 18 19940701 Jul 1,1994 II.D.2. Work group review date added
654 Benzo[a]pyrene (BaP) 50-32-8 19 19941101 Nov 1,1994 II.B.1. Slope factor clarified changed O to %220%22
655 Benzo[a]pyrene (BaP) 50-32-8 20 19950801 Aug 1,1995 II.D.2. EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS review. The IRIS Pilot Program replaced the workgroup functions beginning in September, 1995.
656 Benzo[a]pyrene (BaP) 50-32-8 21 19940301 Mar 1,1994 II. Pending change note removed no change
657 Benzo[a]pyrene (BaP) 50-32-8 22 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
658 Benzo[a]pyrene (BaP) 50-32-8 23 20170119 Jan 19,2017 All EPA completed a reassessment, updating all values.
659 Benzo[a]pyrene (BaP) 50-32-8 24 20180511 May 11,2018 TR Supplemental Info An error was corrected in Table E-1 of the supplemental information document based on a comment from the IRIS hotline. See errata sheet for additional details.
660 Benzo[a]pyrene (BaP) 50-32-8 25 20180802 Aug 2,2018 Key Values WOE Note Added a note regarding ADAF to both the OSF and IUR entries to further explain what is in the tox review.
661 Benzo[a]pyrene (BaP) 50-32-8 26 20200714 Jul 14,2020 Related Topics Added Chemicals Dashboard link
662 Benzo[b]fluoranthene 205-99-2 1 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
663 Benzo[g,h,i]perylene 191-24-2 1 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
664 Benzo[k]fluoranthene 207-08-9 1 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
665 Benzoic acid 65-85-0 1 20180927 Sep 27,2018 Noncancer Critical Updated the system from none to other so it would show up in the advanced search.
666 Benzoic acid 65-85-0 2 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
667 Benzotrichloride 98-07-7 1 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
668 Benzyl chloride 100-44-7 1 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
669 Beryllium and compounds 7440-41-7 1 19880301 Mar 1,1988 I.A.1. Reference dose table clarified
670 Beryllium and compounds 7440-41-7 2 19880301 Mar 1,1988 I.A.2. Text added
671 Beryllium and compounds 7440-41-7 3 19880907 Sep 7,1988 II. Carcinogen summary on-line
672 Beryllium and compounds 7440-41-7 4 19900101 Jan 1,1990 II.A.2. References clarified
673 Beryllium and compounds 7440-41-7 5 19900101 Jan 1,1990 II.A.3. Text revised
674 Beryllium and compounds 7440-41-7 6 19900101 Jan 1,1990 II.B. Quanititative estimate for oral exposure section added
675 Beryllium and compounds 7440-41-7 7 19900101 Jan 1,1990 II.C.3. Text revised
676 Beryllium and compounds 7440-41-7 8 19900101 Jan 1,1990 II.D.2. Work group review dates and verification date added
677 Beryllium and compounds 7440-41-7 9 19900101 Jan 1,1990 VI. Bibliography on-line
678 Beryllium and compounds 7440-41-7 10 19900201 Feb 1,1990 VI.A. Puzanova et al. 1978 citation corrected
679 Beryllium and compounds 7440-41-7 11 19900201 Feb 1,1990 VI.C. Wagner et al. 1969 citation corrected
680 Beryllium and compounds 7440-41-7 12 19900901 Sep 1,1990 I.A. Morgareidge ref. now Cox (same study-authors reversed)
681 Beryllium and compounds 7440-41-7 13 19900901 Sep 1,1990 IV.F.1. EPA contact changed
682 Beryllium and compounds 7440-41-7 14 19900901 Sep 1,1990 VI.A. Morgareidge ref. now Cox (same study-authors reversed)
683 Beryllium and compounds 7440-41-7 15 19910101 Jan 1,1991 II. Text edited
684 Beryllium and compounds 7440-41-7 16 19910101 Jan 1,1991 II.C.1. Inhalation slope factor removed (global change)
685 Beryllium and compounds 7440-41-7 17 19920101 Jan 1,1992 IV. Regulatory actions updated
686 Beryllium and compounds 7440-41-7 18 19920901 Sep 1,1992 II.A.3. U.S. EPA citation year corrected, paragraph 3
687 Beryllium and compounds 7440-41-7 19 19920901 Sep 1,1992 II.D.1. Source document year corrected
688 Beryllium and compounds 7440-41-7 20 19920901 Sep 1,1992 II.D.1. Review statement revised
689 Beryllium and compounds 7440-41-7 21 19920901 Sep 1,1992 VI.C. U.S. EPA reference year corrected
690 Beryllium and compounds 7440-41-7 22 19930201 Feb 1,1993 I.A.7. Primary contact changed
691 Beryllium and compounds 7440-41-7 23 19980403 Apr 3,1998 I.A. Oral RfD Assessment
692 Beryllium and compounds 7440-41-7 24 19980403 Apr 3,1998 I.B. Inhalation RfC Assessment
693 Beryllium and compounds 7440-41-7 25 19980403 Apr 3,1998 II. Carcinogenicity Assessment
694 Beryllium and compounds 7440-41-7 26 19950801 Aug 1,1995 II.D.2. EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS review. the IRIS Pilot Program replaced the workgroup functions beginning in September, 1995.
695 Beryllium and compounds 7440-41-7 27 19970401 Apr 1,1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were remvoed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
696 Beryllium and compounds 7440-41-7 28 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
697 Bidrin 141-66-2 1 20160715 Jul 15,2016 Archived Chemical IRIS working with OPP agreed to mark this pesticide chemical archived.
698 Bidrin 141-66-2 2 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
699 Biphenthrin 82657-04-3 1 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
700 Biphenyl 92-52-4 1 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
701 Bis(2-chloro-1-methylethyl) ether 108-60-1 1 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
702 Bis(2-chloroethoxy)methane 111-91-1 1 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
703 Bis(chloroethyl)ether (BCEE) 111-44-4 1 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
704 Bis(chloromethyl)ether (BCME) 542-88-1 1 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
705 Bisphenol A 80-05-7 1 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
706 Boron and Compounds 7440-42-8 1 None None
707 Boron and Compounds 7440-42-8 2 I.A., I.B., II Revised RfD, added RfC discussion and added carcinogenicity assessment.
708 Boron and Compounds 7440-42-8 3 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
709 Bromate 15541-45-4 1 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
710 Brominated dibenzofurans None 1 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
711 Bromobenzene 108-86-1 1 20090930 Sep 30,2009 I., II. File first on-line.
712 Bromobenzene 108-86-1 2 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
713 Bromochloromethane 74-97-5 1 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
714 Bromodichloromethane 75-27-4 1 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
715 p-Bromodiphenyl ether 101-55-3 1 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
716 Bromoform 75-25-2 1 20200715 Jul 15,2020 Related Topics Added Chemicals Dashboard link
717 Bromomethane 74-83-9 1 19870930 Sep 30,1987 I.A.1. MF changed to UF -- no change in RfD
718 Bromomethane 74-83-9 2 19870930 Sep 30,1987 I.A.2. Text changes
719 Bromomethane 74-83-9 3 19870930 Sep 30,1987 I.A.3. Text changes
720 Bromomethane 74-83-9 4 19870930 Sep 30,1987 I.A.4. Study descriptions added
721 Bromomethane